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Article

The Shh coreceptor Cdo is required for differentiation of midbrain dopaminergic neurons.

Stem cell research - 1 Sept 2014

Kwon Yu-Rim, Jeong Myong-Ho, Leem Young-Eun, Lee Sang-Jin, Kim Hyun-Jin, Bae Gyu-Un, Kang Jong-Sun

Abstract excerpt

Sonic hedgehog (Shh) signaling is required for numerous developmental processes including specification of ventral cell types in the central nervous system such as midbrain dopaminergic (DA) neurons. The multifunctional coreceptor Cdo increases the signaling activity of Shh which is crucial for development of forebrain and neural tube. In this study, we investigated the role of Cdo in midbrain DA neurogenesis....

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Identifiers

PMID: 25117422
DOI: 10.1016/j.scr.2014.07.004

Genes

MAP2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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