Article
The emergent design of the neural tube: prepattern, SHH morphogen and GLI code.
Current opinion in genetics & development - 1 Oct 2003
Ruiz i Altaba Ariel, Nguyên Vân, Palma Verónica
Abstract excerpt
The Sonic hedgehog (Shh) pathway plays an important role in the development of many tissues and organs. The secreted ligand Shh has been shown to act as a mitogen, morphogen and survival factor in different contexts whereas the three Gli transcription factors act as Shh mediators in a context-dep...
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