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Article

Role of Shh in the development of molecularly characterized tegmental nuclei in mouse rhombomere 1.

Brain structure & function - 1 May 2014

Moreno-Bravo J A, Perez-Balaguer A, Martinez-Lopez J E, Aroca P, Puelles L, Martinez S, Puelles E

Abstract excerpt

Hindbrain rhombomeres in general are differentially specified molecularly by unique combinations of Hox genes with other developmental genes. Rhombomere 1 displays special features, including absence of Hox gene expression. It lies within the hindbrain range of the Engrailed genes (En1, En2), controlled by the isthmic organizer via diffusion of FGF8. It is limited rostrally by the isthmus territory, and caudally...

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Source

Identifiers

PMID: 23494735
DOI: 10.1007/s00429-013-0534-6

Genes

FGF8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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