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Article

Role of neuroepithelial Sonic hedgehog in hypothalamic patterning.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 27 May 2009

Szabó Nora-Emöke, Zhao Tianyu, Cankaya Murat, Theil Thomas, Zhou Xunlei, Alvarez-Bolado Gonzalo

Abstract excerpt

The hypothalamus is a region of the diencephalon with particularly complex patterning. Sonic hedgehog (Shh), encoding a protein with key developmental roles, shows a peculiar and dynamic diencephalic expression pattern. Here, we use transgenic strategies and in vitro experiments to test the hypothesis that Shh expressed in the diencephalic neuroepithelium (neural Shh) coordinates tissue growth and patterning in...

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Identifiers

PMID: 19474326
DOI: 10.1523/JNEUROSCI.1089-09.2009
PMCID: PMC6665591

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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