Article
Fitness cost of antibiotic susceptibility during bacterial infection.
Science translational medicine - 22 Jul 2015
Roux Damien, Danilchanka Olga, Guillard Thomas, Cattoir Vincent, Aschard Hugues, Fu Yang, Angoulvant Francois, Messika Jonathan, Ricard Jean-Damien, Mekalanos John J, Lory Stephen, Pier Gerald B, Skurnik David
Abstract excerpt
Advances in high-throughput DNA sequencing allow for a comprehensive analysis of bacterial genes that contribute to virulence in a specific infectious setting. Such information can yield new insights that affect decisions on how to best manage major public health issues such as the threat posed by increasing antimicrobial drug resistance. Much of the focus has been on the consequences of the selective advantage...
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