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Article

Polymorphisms of MMP-2 gene are associated with systolic heart failure risk in Han Chinese.

The American journal of the medical sciences - 1 May 2009

Hua Yihong, Song Li, Wu Naqiong, Lu Xiangfeng, Meng Xianmin, Gu Dongfeng, Yang Yuejin

Abstract excerpt

BACKGROUND: Matrix metalloproteinases (MMPs) are a family of proteolytic enzymes responsible for protein degradation. MMP-2 has been demonstrated to play a pivotal role in myocardial remodeling process that occurs in congestive heart failure (HF). We hypothesized that MMP-2 genetic variations could be associated with systolic HF risk. METHODS: To test the association of single nucleotide polymorphisms of MMP-2...

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PMID: 19295411
DOI: 10.1097/MAJ.0b013e31818eb2a2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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