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Article

MMP-2 and TIMP-2 gene polymorphisms and susceptibility to atrial fibrillation in Chinese Han patients with hypertensive heart disease.

Clinica chimica acta; international journal of clinical chemistry - 2 May 2010

Gai Xiaobo, Zhang Zhigang, Liang Yonggang, Chen Zheming, Yang Xiangyue, Hou Jiake, Lan Xiaopeng, Zheng Weixing, Hou Jianping, Huang Mingfang

Abstract excerpt

BACKGROUND: MMP-2 and TIMP-2 play important roles in the pathogenesis of arrhythmogenic atrial remodeling, and may contribute to the development and persistence of atrial fibrillation (AF). Functional polymorphisms in the promoter of MMP-2 and TIMP-2 gene may modulate an individual's susceptibili...

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Source

Identifiers

PMID: 20138860
DOI: 10.1016/j.cca.2010.02.002

Genes

MMP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20138860-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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