Article
Association between MMP2 gene polymorphisms and dilated cardiomyopathy in a Chinese Han population.
ESC heart failure - 1 Jun 2023
Li Shiyang, Zeng Xiaobin, Wang Shihai, Xie Xiaoshuang, Lan Jianjun
Abstract excerpt
AIMS: Dilated cardiomyopathy (DCM) belongs to the common types of cardiomyopathies. The pathogenesis remains unclear despite the fact that various genes have been found associated with DCM. MMP2 is a zinc-dependent and calcium-containing secreted endoproteinases, which could cleave a broad spectrum of substrates including extracellular matrix components and cytokines. It has proved to play an important role in...
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