Article
Association of MMP-2 gene haplotypes with thoracic aortic dissection in chinese han population.
BMC cardiovascular disorders - 14 Jan 2016
Liu Ou, Li Jiachen, Xin Yi, Qin Yanwen, Li Haiyang, Gong Ming, Liu Yuyong, Wang Xiaolong, Li Jianrong, Zhang Hongjia
Abstract excerpt
BACKGROUND: Thoracic aortic dissection (TAD) is the most common life-threatening disorder, and MMP-2 is involved in TAD pathogenesis. Our purpose is to systematically evaluate the association of the MMP-2 gene with TAD risk in Chinese Han population. METHODS: In our case-control study, we recruited 755 unrelated participants: 315 case participants with TAD and 440 controls. Twenty-two tag SNPs were selected from...
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