Article
Matrix Metalloproteinase-2 Polymorphisms in Chronic Heart Failure: Relationship with Susceptibility and Long-Term Survival.
PloS one - 1 Jan 2016
Beber Ana Rubia C, Polina Evelise R, Biolo Andréia, Santos Bruna L, Gomes Daiane C, La Porta Vanessa L, Olsen Virgílio, Clausell Nadine, Rohde Luis E, Santos Kátia G
Abstract excerpt
Circulating levels of matrix metalloproteinase-2 (MMP-2) predict mortality and hospital admission in heart failure (HF) patients. However, the role of MMP-2 gene polymorphisms in the susceptibility and prognosis of HF remains elusive. In this study, 308 HF outpatients (216 Caucasian- and 92 African-Brazilians) and 333 healthy subjects (256 Caucasian- and 77 African-Brazilians) were genotyped for the -1575G>A...
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