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Article

Polymorphisms of matrix metalloproteinases in systolic heart failure: role on disease susceptibility, phenotypic characteristics, and prognosis.

Journal of cardiac failure - 1 Feb 2011

Velho Fábio M, Cohen Carolina R, Santos Kátia G, Silvello Daiane, Martinelli Nidiane, Biolo Andréia, Clausell Nadine, Rohde Luis E

Abstract excerpt

BACKGROUND: The role of matrix metalloproteinases (MMPs) polymorphisms on heart failure (HF) susceptibility, phenotypic characteristics, and prognosis has been poorly explored. METHODS AND RESULTS: We studied 313 HF patients with left ventricular systolic dysfunction and 367 healthy control subjects. Genotyping of MMP-1 (-1607 1G/2G), MMP-3 (-1171 5A/6A), and MMP-9 (-1562 C/T) polymorphisms was performed by...

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Source

Identifiers

PMID: 21300300
DOI: 10.1016/j.cardfail.2010.09.017

Genes

MMP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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