Article
The role of matrix metalloproteinase-2 promoter polymorphisms in coronary artery disease and myocardial infarction.
Genetic testing and molecular biomarkers - 1 Apr 2011
Alp Ebru, Menevse Sevda, Tulmac Murat, Yilmaz Akin, Yalcin Ridvan, Cengel Atiye
Abstract excerpt
The matrix metalloproteinase (MMP) family are key enzymes involved in the breakdown of the extracellular matrix in normal physiological processes, including tissue remodeling, and disease processes, such as arthritis and metastasis. The promoter polymorphism in the MMP2 gene may be responsible for multiple diseases related to extracellular matrix degradation. Therefore, we aimed to investigate the relationship...
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