Article
Polymorphisms of MMP-2 gene are associated with systolic heart failure prognosis.
Clinica chimica acta; international journal of clinical chemistry - 27 Jun 2009
Hua Yihong, Song Li, Wu Naqiong, Xie Gaoqiang, Lu Xiangfeng, Fan Xiaohan, Meng Xianmin, Gu Dongfeng, Yang Yuejin
Abstract excerpt
BACKGROUND: MMP-2 is a proteolytic enzyme involved in myocardial remodeling that occurs in congestive heart failure (HF). We hypothesized MMP-2 genetic variations could influence the prognosis of systolic HF. METHODS: To test our hypothesis, we performed a follow-up study of 605 patients with sys...
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