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Article

Polymorphisms of MMP-2 gene are associated with systolic heart failure prognosis.

Clinica chimica acta; international journal of clinical chemistry - 27 Jun 2009

Hua Yihong, Song Li, Wu Naqiong, Xie Gaoqiang, Lu Xiangfeng, Fan Xiaohan, Meng Xianmin, Gu Dongfeng, Yang Yuejin

Abstract excerpt

BACKGROUND: MMP-2 is a proteolytic enzyme involved in myocardial remodeling that occurs in congestive heart failure (HF). We hypothesized MMP-2 genetic variations could influence the prognosis of systolic HF. METHODS: To test our hypothesis, we performed a follow-up study of 605 patients with systolic HF. Three single nucleotide polymorphisms (SNPs) of MMP-2 (rs243864, rs243866, rs17859821) were analyzed by...

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PMID: 19332048
DOI: 10.1016/j.cca.2009.03.030

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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