Article
Leukotriene C4 synthase and ischemic cardiovascular disease and obstructive pulmonary disease in 13,000 individuals.
Journal of molecular and cellular cardiology - 1 Apr 2009
Freiberg Jacob J, Dahl Morten, Tybjaerg-Hansen Anne, Grande Peer, Nordestgaard Børge G
Abstract excerpt
Ischemic cardiovascular disease and obstructive pulmonary disease involve inflammation. Leukotrienes may be important pro-inflammatory mediators. We tested the hypothesis that the (-1072)G > A and (-444)A > C promoter polymorphisms of leukotriene C4 synthase confer risk of transient ischemic atta...
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