Genetic variation in members of the leukotrienes biosynthesis pathway confers risk of ischemic stroke in Eastern Han Chinese.

doi:10.1016/j.plefa.2012.09.005

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Genetic variation in members of the leukotrienes biosynthesis pathway confers risk of ischemic stroke in Eastern Han Chinese.

Prostaglandins, leukotrienes, and essential fatty acids - 1 Dec 2012

Wang Gannan, Zhang Jinsong, Sun Hao, Cao Weijuan, Zhang Jing, Wang Yao, Xiao Hang

Abstract excerpt

This study was aimed to explore the association of genetic variation in members of the leukotrienes biosynthesis pathway as potential mediators with ischemic stroke (IS) risk in Eastern Han Chinese. A case-control study of was conducted with five selected single nucleotide polymorphisms (SNPs). In the single-locus analysis, carriers of C allele of rs730012 in LTC4S were more susceptible to IS (OR, 1.28; 95% CI,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Arachidonate 5-Lipoxygenase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Asian People

Share to Brain Ischemia

Share to Epoxide Hydrolases

Share to Genes, Recessive

Share to Glutathione Transferase

Share to Leukotrienes

Share to Stroke

Source

Open in PubMed

Identifiers

PMID: 23079278
DOI: 10.1016/j.plefa.2012.09.005

Genes

ALOX5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic variation in members of the leukotrienes biosynthesis pathway confers risk of ischemic stroke in Eastern Han Chinese.PMID 23079278Read ↗

Association between genetic variants of the leukotriene biosynthesis pathway and the risk of stroke: a case-control study in the Chinese Han population.Semantic proximity Read ↗

Genetic variants in the promoter region of the ALOX5AP gene and susceptibility of ischemic stroke.Semantic proximity Read ↗

[Study on the association between leukotriene A4 hydrolase gene polymorphism and ischemic stroke].Semantic proximity Read ↗

Variants in the Atherogenic ALOX5AP, THBD, and KNG1 Genes Potentiate the Risk of Ischemic Stroke via a Genetic Main Effect and Epistatic Interactions in a Chinese Population.Semantic proximity Read ↗

Arachidonate 5-lipoxygenase-activating protein (ALOX5AP) gene rs4073259 polymorphism not associated with ischemic stroke in the northeastern Chinese Han population.Semantic proximity Read ↗

A promoter polymorphism (rs17222919, -1316T/G) of ALOX5AP gene is associated with decreased risk of ischemic stroke in two independent Chinese populations.Semantic proximity Read ↗

Interaction between ALOX5AP and CYP3A5 gene variants significantly increases the risk for cerebral infarctions in Chinese.Semantic proximity Read ↗

ALOX5AP genetic variants and risk of atherothrombotic stroke in the Taiwanese population.Semantic proximity Read ↗

Genetic variation in members of the leukotriene biosynthesis pathway confer an increased risk of ischemic stroke: a replication study in two independent populations.Semantic proximity Read ↗

Association of ALOX5AP1 SG13S114T/A variant with ischemic stroke, stroke subtypes and aspirin resistance.Semantic proximity Read ↗

Polymorphism of SG13S114T/A in the ALOX5AP gene and the risk for stroke in a large Chinese cohort.Semantic proximity Read ↗

Expression analysis of leukotriene-inflammatory gene interaction network in patients with coronary artery disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.