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Article

Common Polymorphisms in the 5-Lipoxygenase Pathway and Risk of Incident Myocardial Infarction: A Danish Case-Cohort Study.

PloS one - 1 Jan 2016

Gammelmark Anders, Nielsen Michael S, Lundbye-Christensen Søren, Tjønneland Anne, Schmidt Erik B, Overvad Kim

Abstract excerpt

BACKGROUND: The 5-lipoxygenase pathway (5-LOX) has been implicated in the development of cardiovascular disease and studies have suggested that genetic polymorphisms related to key enzymes in this pathway may confer risk of myocardial infarction (MI). This study investigated the association of pre-selected genetic polymorphisms in four candidate genes of 5-LOX (arachidonate 5-lipoxygenase and its activating...

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Identifiers

PMID: 27893808
DOI: 10.1371/journal.pone.0167217
PMCID: PMC5125697

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LOX

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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