Article
Novel mutations in leukotriene C4 synthase and risk of cardiovascular disease based on genotypes from 50,000 individuals.
Journal of thrombosis and haemostasis : JTH - 1 Aug 2010
Freiberg J J, Tybjaerg-Hansen A, Nordestgaard B G
Abstract excerpt
BACKGROUND: Atherosclerosis is an inflammatory condition where cysteinyl leukotrienes have been identified to play an important role. Furthermore, cysteinyl leukotrienes may also affect thrombus formation. Using prospective, cross-sectional and case-control designs, we tested the hypothesis that...
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