Association of PLA2G4A with myocardial infarction is modulated by dietary PUFAs.

doi:10.3945/ajcn.111.032094

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Article

Association of PLA2G4A with myocardial infarction is modulated by dietary PUFAs.

The American journal of clinical nutrition - 1 Apr 2012

Hartiala Jaana, Gilliam Elizabeth, Vikman Susanna, Campos Hannia, Allayee Hooman

Abstract excerpt

BACKGROUND: Leukotrienes are proinflammatory molecules derived from dietary PUFAs and have been associated with cardiovascular disease (CVD). We previously reported that an A→G variant (rs12746200) of the cytosolic phospholipase A2 group IVA gene (PLA2G4A), which encodes the enzyme that liberates PUFAs from cellular membranes for leukotriene synthesis, decreases the risk of CVD. OBJECTIVE: We sought to replicate...

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PMID: 22378731
DOI: 10.3945/ajcn.111.032094
PMCID: PMC3302367

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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