Article
Expression analysis of leukotriene-inflammatory gene interaction network in patients with coronary artery disease.
Journal of atherosclerosis and thrombosis - 1 Jan 2014
Nair Jiny, Shanker Jayashree, Jambunathan Srikarthika, Arvind Prathima, Kakkar Vijay V
Abstract excerpt
AIM: Leukotrienes are important lipid inflammatory mediators that play a pivotal role in the pathogenesis of atherosclerosis. We aimed to construct a network of interactions between leukotrienes and inflammatory biomarkers and evaluate the expression of key members of the leukotriene pathway and leukotriene-induced inflammatory molecules in patients with coronary artery disease (CAD) and healthy controls....
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