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Article

Promotor polymorphisms in leukotriene C4 synthase and risk of ischemic cerebrovascular disease.

Arteriosclerosis, thrombosis, and vascular biology - 1 May 2008

Freiberg Jacob J, Tybjaerg-Hansen Anne, Sillesen Henrik, Jensen Gorm B, Nordestgaard Børge G

Abstract excerpt

OBJECTIVE: Cysteinyl leukotrienes are involved in inflammation and possibly in early carotid atherosclerosis. We tested the hypothesis that the -444 A/C and -1072 G/A polymorphisms of the leukotriene C(4) synthase associate with risk of ischemic cerebrovascular disease. METHODS AND RESULTS: We genotyped 10 592 individuals from the Danish general population, the Copenhagen City Heart Study. During 24 years of...

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Identifiers

PMID: 18276912
DOI: 10.1161/ATVBAHA.107.158873

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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