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Article

Genetic variation in members of the leukotriene biosynthesis pathway confer an increased risk of ischemic stroke: a replication study in two independent populations.

Stroke - 1 Apr 2008

Bevan Steve, Dichgans Martin, Wiechmann H Erich, Gschwendtner Andreas, Meitinger Thomas, Markus Hugh S

Abstract excerpt

BACKGROUND AND PURPOSE: The recent finding that genetic variants in 5-lipoxygenase activating protein and leukotriene A4 hydrolase may confer an increased risk of ischemic stroke has implicated the leukotriene family as potential mediators of cardiovascular disease. Using a case control replication methodology, all members of the leukotriene synthesis pathway and their receptors were examined for genetic...

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Identifiers

PMID: 18323512
DOI: 10.1161/STROKEAHA.107.491969

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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