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Article

Interactions among genes influencing bacterial recognition increase IBD risk in a population-based New Zealand cohort.

Human immunology - 1 Jun 2009

Petermann Ivonne, Huebner Claudia, Browning Brian L, Gearry Richard B, Barclay Murray L, Kennedy Martin, Roberts Rebecca, Shelling Andrew N, Philpott Martin, Han Dug Yeo, Ferguson Lynnette R

Abstract excerpt

Bacterial sensing is crucial for appropriate response by the innate and adaptive immune system against invading microorganisms. Single nucleotide polymorphisms (SNPs) in genes involved in bacterial recognition, CARD15 and TLR4, increased the risk of inflammatory bowel disease (IBD) in a New Zealand Caucasian case-control cohort. We now consider the effects of SNPs in CD14, TLR9, and BPI, analyzed individually, in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19275920
DOI: 10.1016/j.humimm.2009.03.002

Genes

BPI
TLR4
TLR9

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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