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Article

Polymorphisms of CARD15/NOD2 and CD14 genes in New Zealand Crohn's disease patients.

Immunology and cell biology - 1 Oct 2005

Leung Euphemia, Hong Jiwon, Fraser Alan G, Merriman Tony R, Vishnu Prakash, Abbott William G H, Krissansen Geoffrey W

Abstract excerpt

Polymorphisms in the CARD15/NOD2 gene, which encodes a cytosolic protein involved in bacterial recognition, are associated with development of Crohn's disease (CD). Other potential susceptibility genes such as CD14 may compound the risk of developing CD. We examined the frequency of the three major CARD15 risk alleles (3020insC/L1007fsinsC, G908R and R702W), and a functional polymorphism (-159C/T) in the promoter...

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Source

Identifiers

PMID: 16174099
DOI: 10.1111/j.1440-1711.2005.01362.x

Genes

NOD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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