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Article

Tolllike receptor 4 (TLR4) polymorphisms in Tunisian patients with Crohn's disease: genotype-phenotype correlation.

BMC gastroenterology - 7 Aug 2009

Zouiten-Mekki Lilia, Kharrat Maher, Karoui Sami, Serghimi Mariem, Fekih Monia, Matri Samira, Kallel Lamia, Boubaker Jalel, Filali Azza, Chaabouni Habiba

Abstract excerpt

BACKGROUND: The immune responses to bacterial products through the pattern recognition receptor (PRR) play a pivotal role in pathogenesis of Crohn's disease. A recent study described an association between CD and some gene coding for bacterial receptor like NOD2/CARD15 gene and TLR4. In this study, we sought to determine whether TLR4 gene was associated with Crohn's disease (CD) among the Tunisian population and...

Topics

Adult
Case-Control Studies
Crohn Disease
Female
Gene Frequency
Genetic Predisposition to Disease
Genotype
Humans
Male
Phenotype
Polymorphism, Single Nucleotide

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Toll-Like Receptor 4

Tunisia

Source

Open in PubMed Open full text

Identifiers

PMID: 19664207
DOI: 10.1186/1471-230X-9-62
PMCID: PMC2736969

Genes

TLR4
NOD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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Tolllike receptor 4 (TLR4) polymorphisms in Tunisian patients with Crohn's disease: genotype-phenotype correlation.PMID 19664207Read ↗

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