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Article

Genetic variation within TLR10 is associated with Crohn's disease in a New Zealand population.

Human immunology - 1 Apr 2012

Morgan Angharad R, Lam Wen-Jiun, Han Dug-Yeo, Fraser Alan G, Ferguson Lynnette R

Abstract excerpt

Toll-like receptors (TLRs) play an important role in the induction and regulation of the innate immune system and have been implicated in both infectious and inflammatory diseases. Recently the first association of TLR10 with Crohn's disease (CD) was reported. Here, we attempted to validate this association, using a candidate gene single nucleotide polymorphism (SNP) study of TLR10 in CD. We identified tagging...

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Source

Identifiers

PMID: 22342453
DOI: 10.1016/j.humimm.2012.01.015

Genes

TLR10

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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