Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Lack of association of the CD14 promoter polymorphism--159C/T with Caucasian inflammatory bowel disease.

Scandinavian journal of gastroenterology - 1 Feb 2005

Peters Kirsten E, O'Callaghan Nathan J, Cavanaugh Juleen A

Abstract excerpt

OBJECTIVE: The inflammatory bowel diseases (IBDs), including Crohn's disease (CD) and ulcerative colitis (UC), are multifactorial diseases resulting from a complex interaction of genetic and environmental factors. The recently described CARD15 and TNF-alpha risk alleles are believed to be contributors to disease by disrupting inflammatory pathways via impaired response to bacteria. Other bacterial receptors, such...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Australia
Share to Inflammatory Bowel Diseases

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Intracellular Signaling Peptides and Proteins

Share to Lipopolysaccharide Receptors

Share to Nod2 Signaling Adaptor Protein

Share to Promoter Regions, Genetic

Share to Tumor Necrosis Factor-alpha

Share to White People

Source

Identifiers

PMID: 15764151
DOI: 10.1080/00365520510011506

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Lack of association of the CD14 promoter polymorphism--159C/T with Caucasian inflammatory bowel disease.PMID 15764151Read ↗

Ulcerative colitis is associated with a promoter polymorphism of lipopolysaccharide receptor gene, CD14.Semantic proximity Read ↗

A polymorphism in the CD14 gene is associated with Crohn disease.Semantic proximity Read ↗

The c.1-260C>T promoter variant of CD14 but not the c.896A>G (p.D299G) variant of toll-like receptor 4 (TLR4) genes is associated with inflammatory bowel disease.Semantic proximity Read ↗

Lack of association of the CD14/C-159T polymorphism with susceptibility and serological activity parameters of rheumatoid arthritis.Semantic proximity Read ↗

Polymorphisms of CARD15/NOD2 and CD14 genes in New Zealand Crohn's disease patients.Semantic proximity Read ↗

The CD14 C-159T polymorphism is not associated with asthma or asthma severity in an Australian adult population.Semantic proximity Read ↗

Interaction of polymorphisms in the CARD15 and CD14 genes in patients with Crohn disease.Semantic proximity Read ↗

A promoter polymorphism in the CD14 gene is associated with elevated levels of soluble CD14 but not with IgE or atopic diseases.Semantic proximity Read ↗

Association between the promoter polymorphism T/C at position -159 of the CD14 gene and anti-inflammatory therapy in patients with inflammatory bowel disease.Semantic proximity Read ↗

CARD15/NOD2, CD14 and toll-like 4 receptor gene polymorphisms in Saudi patients with Crohn's Disease.Semantic proximity Read ↗

Interactions among genes influencing bacterial recognition increase IBD risk in a population-based New Zealand cohort.Semantic proximity Read ↗

Promoter region polymorphism of the CD14 gene (C-159T) is not associated with psoriasis vulgaris.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.