Article
Association between polymorphisms in the Toll-like receptor 4, CD14, and CARD15/NOD2 and inflammatory bowel disease in the Greek population.
World journal of gastroenterology - 7 Feb 2005
Gazouli Maria, Mantzaris Gerassimos, Kotsinas Athanassios, Zacharatos Panayotis, Papalambros Efstathios, Archimandritis Athanassios, Ikonomopoulos John, Gorgoulis Vassilis-G
Abstract excerpt
AIM: Crohn's disease (CD) and ulcerative colitis (UC) are multifactorial diseases with a significant genetic background. Apart from CARD15/NOD2 gene, evidence is accumulating that molecules related to the innate immune response such as CD14 or Toll-like receptor 4 (TLR4), are involved in their pathogenesis. In further exploring the genetic background of these diseases, we investigated the variations in the...
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