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Article

Estimating risks of common complex diseases across genetic and environmental factors: the example of Crohn disease.

Journal of medical genetics - 1 Nov 2007

Lewis C M, Whitwell S C L, Forbes A, Sanderson J, Mathew C G, Marteau T M

Abstract excerpt

BACKGROUND: Progress has been made in identifying mutations that confer susceptibility to complex diseases, with the prospect that these genetic risks might be used in determining individual disease risk. AIM: To use Crohn disease (CD) as a model of a common complex disorder, and to develop methods to estimate disease risks using both genetic and environmental risk factors. METHODS: The calculations used three...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 17660460
DOI: 10.1136/jmg.2007.051672
PMCID: PMC2752174

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