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Article

Role of 5'- and 3'-untranslated regions of mRNAs in human diseases.

Biology of the cell - 1 May 2009

Chatterjee Sangeeta, Pal Jayanta K

Abstract excerpt

Protein synthesis is often regulated at the level of initiation of translation, making it a critical step. This regulation occurs by both the cis-regulatory elements, which are located in the 5'- and 3'-UTRs (untranslated regions), and trans-acting factors. A breakdown in this regulation machinery can perturb cellular metabolism, leading to various physiological abnormalities. The highly structured UTRs, along...

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Identifiers

PMID: 19275763
DOI: 10.1042/BC20080104

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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