Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

5' Untranslated Region Elements Show High Abundance and Great Variability in Homologous ABCA Subfamily Genes.

International journal of molecular sciences - 23 Nov 2020

Dvorak Pavel, Hlavac Viktor, Soucek Pavel

Abstract excerpt

The 12 members of the ABCA subfamily in humans are known for their ability to transport cholesterol and its derivatives, vitamins, and xenobiotics across biomembranes. Several ABCA genes are causatively linked to inborn diseases, and the role in cancer progression and metastasis is studied intensively. The regulation of translation initiation is implicated as the major mechanism in the processes of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 5' Untranslated Regions
Share to Biological Transport
Share to Cholesterol

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Multigene Family

Share to Open Reading Frames

Share to Protein Biosynthesis

Share to Ribosomes

Share to Xenobiotics

Source

Open in PubMed Open full text

Identifiers

PMID: 33238634
DOI: 10.3390/ijms21228878
PMCID: PMC7700387

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

5' Untranslated Region Elements Show High Abundance and Great Variability in Homologous ABCA Subfamily Genes.PMID 33238634Read ↗

Role of 5'- and 3'-untranslated regions of mRNAs in human diseases.Semantic proximity Read ↗

Predicting functional UTR variants by integrating region-specific features.Semantic proximity Read ↗

Recent advances in the regulation of ABCA1 and ABCG1 by lncRNAsSemantic proximity Read ↗

A comprehensive catalog of predicted functional upstream open reading frames in humans.Semantic proximity Read ↗

Sequence variations affecting AU-rich element function and disease.Semantic proximity Read ↗

Genome-wide detection of human 5' UTR variants that impact protein translation.Semantic proximity Read ↗

Complete characterization of the human ABC gene family.Semantic proximity Read ↗

ABCA1 mRNA and Protein Distribution Patterns Predict Multiple Different Roles and Levels of RegulationSemantic proximity Read ↗

Widespread separation of the polypyrimidine tract from 3’ AG by G tracts in association with alternative exons in metazoa and plantsSemantic proximity Read ↗

Genetic variants in mRNA untranslated regions.Semantic proximity Read ↗

The C421A (Q141K) polymorphism enhances the 3'-untranslated region (3'-UTR)-dependent regulation of ATP-binding cassette transporter ABCG2.Semantic proximity Read ↗

Alu sequences in the coding regions of mRNA: a source of protein variability.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.