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Article

Polymorphisms of the renin-angiotensin system are associated with blood pressure, atherosclerosis and cerebral white matter pathology.

Journal of neurology, neurosurgery, and psychiatry - 1 Oct 2007

van Rijn M J E, Bos M J, Isaacs A, Yazdanpanah M, Arias-Vásquez A, Stricker B H Ch, Klungel O H, Oostra B A, Koudstaal P J, Witteman J C, Hofman A, Breteler M M B, van Duijn C M

Abstract excerpt

BACKGROUND: The renin-angiotensin system is involved in the development of hypertension, atherosclerosis and cardiovascular disease. We studied the association between the M235T polymorphism of the angiotensinogen gene (AGT) and the C573T polymorphism of the angiotensin II type 1 receptor (AT1R) and blood pressure, carotid atherosclerosis and cerebrovascular disease. METHODS: We genotyped over 6000 subjects from...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 17220293
DOI: 10.1136/jnnp.2006.109819
PMCID: PMC2117548

Genes

AGT

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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