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Article

Renin-angiotensin system genetic polymorphisms and cerebral white matter lesions in essential hypertension.

Hypertension (Dallas, Tex. : 1979) - 1 Feb 2002

Sierra Cristina, Coca Antonio, Gómez-Angelats Elisenda, Poch Esteban, Sobrino Javier, de la Sierra Alejandro

Abstract excerpt

It has been reported that both the DD genotype of the angiotensin converting enzyme (ACE) gene and the presence of cerebral white matter lesions (WML) may represent risk factors for the development of stroke. The present study investigates a possible association between 3 different genetic polymorphisms of the renin-angiotensin system and the presence of WML in 60 never-treated essential hypertensive patients (36...

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Source

Identifiers

PMID: 11882570
DOI: 10.1161/hy02t2.102912

Genes

ACE
AGT

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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