Polymorphisms of cytochrome P450 1A2 and N-acetyltransferase genes, meat consumption, and risk of colorectal cancer.

doi:10.1007/DCR.0b013e31819734d7

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Article

Polymorphisms of cytochrome P450 1A2 and N-acetyltransferase genes, meat consumption, and risk of colorectal cancer.

Diseases of the colon and rectum - 1 Jan 2009

Yeh Chih-Ching, Sung Fung-Chang, Tang Reiping, Chang-Chieh Chung Rong, Hsieh Ling-Ling

Abstract excerpt

PURPOSE: Polymorphic cytochrome P-450 1A2, N-acetyltransferase 1, and 2 are important enzymes involved in the biotransformation of aromatic and heterocyclic amines known as carcinogens for colorectal cancer. A hospital-based study was designed to investigate the association between colorectal cancer and cytochrome P-450 1A2, N-acetyltransferase 1, and N-acetyltransferase 2, with the interaction of meat...

Topics

Acetylation
Arylamine N-Acetyltransferase
Cocarcinogenesis
Colorectal Neoplasms
Cytochrome P-450 CYP1A2
Diet
Genetic Predisposition to Disease
Genotype
Heterocyclic Compounds
Humans
Isoenzymes
Meat
Polymorphism, Genetic
Risk Factors

Source

Open in PubMed

Identifiers

PMID: 19273964
DOI: 10.1007/DCR.0b013e31819734d7

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