Article
Localization of multiple pleiotropic genes for lipoprotein metabolism in baboons.
Journal of lipid research - 1 Jul 2009
Rainwater David L, Cox Laura A, Rogers Jeffrey, VandeBerg John L, Mahaney Michael C
Abstract excerpt
We employed a novel approach to identify the key loci that harbor genes influencing lipoprotein metabolism in approximately 2,000 pedigreed baboons fed various diets differing in levels of fat and cholesterol. In this study, 126 overlapping traits related to both LDL and HDL metabolism were normalized and subjected to genome-wide linkage screening. As was expected, the traits were highly, but not completely,...
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