Article
Genetical genomics of Th1 and Th2 immune response in a baboon model of atherosclerosis risk factors.
Atherosclerosis - 1 Aug 2011
Vinson A, Curran J E, Johnson M P, Dyer T D, Moses E K, Blangero J, Cox L A, Rogers J, Havill L M, Vandeberg J L, Mahaney M C
Abstract excerpt
OBJECTIVE: CD4(+) T-cells mediate inflammation in atherosclerosis, but additive genetic effects on associated pathways of Th1 and Th2 immune response have not been described. We sought to characterize heritability, pleiotropy, and QTL effects on the expression of genes implicated in Th1 and Th2 i...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
