Article

Genetic regulatory effects in response to a high cholesterol, high fat diet in baboons

2023-08-03

Abstract excerpt

<h4>Summary</h4> Steady-state expression quantitative trait loci (eQTLs) explain only a fraction of disease-associated loci identified through genome-wide association studies (GWAS), while eQTLs involved in gene-by-environment (GxE) interactions have rarely been characterized in humans due to experimental challenges. Using a baboon model, we found hundreds of eQTLs that emerge in adipose, liver, and muscle after...

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Literature Corpus work: af03dbb0-918e-523c-b9d4-cbf49e5d32d8
DOI: 10.1101/2023.08.01.551489

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