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Article

Determinants of variation in serum paraoxonase enzyme activity in baboons.

Journal of lipid research - 1 Jul 2005

Rainwater David L, Mahaney Michael C, Wang Xing Li, Rogers Jeffrey, Cox Laura A, Vandeberg John L

Abstract excerpt

Paraoxonase (PON), an HDL-associated enzyme, is one of many circulating antioxidants thought to play a vital protective role. To better understand the determinants of quantitative variation in serum PON activity, we assayed PON in samples from 611 pedigreed baboons fed three diets. PON was measured enzymatically; the main determinant of variation was genetic and consisted of at least three components: two loci...

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Source

Identifiers

PMID: 15834129
DOI: 10.1194/jlr.M400473-JLR200

Genes

PON1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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