Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic regulatory effects in response to a high-cholesterol, high-fat diet in baboons.

Cell genomics - 13 Mar 2024

Lin Wenhe, Wall Jeffrey D, Li Ge, Newman Deborah, Yang Yunqi, Abney Mark, VandeBerg John L, Olivier Michael, Gilad Yoav, Cox Laura A

Abstract excerpt

Steady-state expression quantitative trait loci (eQTLs) explain only a fraction of disease-associated loci identified through genome-wide association studies (GWASs), while eQTLs involved in gene-by-environment (GxE) interactions have rarely been characterized in humans due to experimental challenges. Using a baboon model, we found hundreds of eQTLs that emerge in adipose, liver, and muscle after prolonged...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Diet, High-Fat
Share to Gene Expression Regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome-Wide Association Study

Share to Phenotype

Share to Quantitative Trait Loci

Source

Open in PubMed Open full text

Identifiers

PMID: 38430910
DOI: 10.1016/j.xgen.2024.100509
PMCID: PMC10943580

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic regulatory effects in response to a high-cholesterol, high-fat diet in baboons.PMID 38430910Read ↗

Genetic regulatory effects in response to a high cholesterol, high fat diet in baboonsSemantic proximity Read ↗

An integrated approach to identify environmental modulators of genetic risk factors for complex traits.Semantic proximity Read ↗

An integrated approach to identify environmental modulators of genetic risk factors for complex traitsSemantic proximity Read ↗

BMI-genome interactions regulate global gene expression with emphasis in brain and gut.Semantic proximity Read ↗

The genetic architecture of gene expression levels in wild baboons.Semantic proximity Read ↗

A cross-population compendium of gene-environment interactions.Semantic proximity Read ↗

Unraveling the regulatory mechanisms underlying tissue-dependent genetic variation of gene expression.Semantic proximity Read ↗

Genetic effects on chromatin accessibility uncover mechanisms of liver gene regulation and quantitative traits.Semantic proximity Read ↗

Genetic Mapping of Multiple Traits Identifies Novel Genes for Adiposity, Lipids, and Insulin Secretory Capacity in Outbred Rats.Semantic proximity Read ↗

Localization of multiple pleiotropic genes for lipoprotein metabolism in baboons.Semantic proximity Read ↗

Genetic Architecture of Gene Expression in European and African Americans: An eQTL Mapping Study in GENOA.Semantic proximity Read ↗

Disease-associated loci share properties with response eQTLs under common environmental exposuresSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.