Article
Identification of candidate genes regulating HDL cholesterol using a chromosomal region expression array.
Genome research - 1 Nov 2002
Cox Laura A, Birnbaum Shifra, VandeBerg John L
Abstract excerpt
To identify candidate genes encoding QTLs in baboons, we have developed a novel strategy that integrates comparative mapping, bioinformatics, and expression arrays. A genome-wide scan, performed previously on pedigreed baboons to localize QTLs for phenotypes that are known risk factors for atherosclerosis, revealed a QTL on chromosome 18q that influences high-density lipoprotein cholesterol (HDL-C) phenotypes....
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