Article
Two major loci control variation in beta-lipoprotein cholesterol and response to dietary fat and cholesterol in baboons.
Arteriosclerosis, thrombosis, and vascular biology - 1 Jul 1998
Rainwater D L, Kammerer C M, Hixson J E, Carey K D, Rice K S, Dyke B, VandeBerg J F, Slifer S H, Atwood L D, McGill H C, Vandeberg J L
Abstract excerpt
We explored the genetic control of cholesterolemic responses to dietary cholesterol and fat in 575 pedigreed baboons. We measured cholesterol in beta-lipoproteins (low density lipoprotein cholesterol [LDLC]) in blood drawn from baboons while they were consuming a baseline (low in cholesterol and fat) diet, a high-saturated fat (lard) diet, and a high-cholesterol, high-saturated fat diet. In addition to baseline...
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