Article
Functional complementation studies identify candidate genes and common genetic variants associated with ovarian cancer survival.
Human molecular genetics - 15 May 2009
Quaye Lydia, Dafou Dimitra, Ramus Susan J, Song Honglin, Gentry-Maharaj Aleksandra, Maharaj Aleksandra Gentry, Notaridou Maria, Hogdall Estrid, Kjaer Susanne Kruger, Christensen Lise, Hogdall Claus, Easton Douglas F, Jacobs Ian, Menon Usha, Pharoah Paul D P, Gayther Simon A
Abstract excerpt
Common germline genetic variation and/or somatic alterations in tumours may be associated with survival in women diagnosed with ovarian cancer. The successful identification of genetic associations relies on a suitable strategy for identifying and testing candidate genes. We used microcell-mediated chromosome transfer approach and expression microarray analysis to identify genes that were associated with...
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