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Article

Genetic background of different cancer cell lines influences the gene set involved in chromosome 8 mediated breast tumor suppression.

Genes, chromosomes & cancer - 1 Jun 2006

Seitz Susanne, Korsching Eberhard, Weimer Jörg, Jacobsen Anja, Arnold Norbert, Meindl Alfons, Arnold Wolfgang, Gustavus Dirk, Klebig Christiane, Petersen Iver, Scherneck Siegfried

Abstract excerpt

Several lines of evidence suggest that chromosome 8 is likely to harbor tumor-suppressor genes involved in breast cancer. We showed previously that microcell-mediated transfer of human chromosome 8 into breast cancer cell line MDA-MB-231 resulted in reversion of these cells to tumorigenicity and was accompanied by changes in the expression of a breast cancer-relevant gene set. In the present study, we...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16552773
DOI: 10.1002/gcc.20325

Genes

CRYAB
MYH11
PDGFRL
PLAGL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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