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Article

Genetic variants in telomere-maintenance genes are associated with ovarian cancer risk and outcome.

Journal of cellular and molecular medicine - 1 Mar 2017

Sun Yuhui, Tao Wade, Huang Maosheng, Wu Xifeng, Gu Jian

Abstract excerpt

Most ovarian cancer patients present at an advanced stage with poor prognosis. Telomeres play a critical role in protecting chromosomes stability. The associations of genetic variants in telomere maintenance genes and ovarian cancer risk and outcome are unclear. We genotyped 137 single nucleotide polymorphisms (SNPs) in telomere-maintenance genes in 417 ovarian cancer cases and 417 matched healthy controls to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28233473
DOI: 10.1111/jcmm.12995
PMCID: PMC5323825

Genes

TEP1
TNKS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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