Article
Common alleles in candidate susceptibility genes associated with risk and development of epithelial ovarian cancer.
International journal of cancer - 1 May 2011
Notaridou Maria, Quaye Lydia, Dafou Dimitra, Jones Chris, Song Honglin, Høgdall Estrid, Kjaer Susanne K, Christensen Lise, Høgdall Claus, Blaakaer Jan, McGuire Valerie, Wu Anna H, Van Den Berg David J, Pike Malcolm C, Gentry-Maharaj Aleksandra, Wozniak Eva, Sher Tanya, Jacobs Ian J, Tyrer Jonathan, Schildkraut Joellen M, Moorman Patricia G, Iversen Edwin S, Jakubowska Anna, Mędrek Krzysztof, Lubiński Jan, Ness Roberta B, Moysich Kirsten B, Lurie Galina, Wilkens Lynne R, Carney Michael E, Wang-Gohrke Shan, Doherty Jennifer A, Rossing Mary Anne, Beckmann Matthias W, Thiel Falk C, Ekici Arif B, Chen Xiaoqing, Beesley Jonathan, Gronwald Jacek, Fasching Peter A, Chang-Claude Jenny, Goodman Marc T, Chenevix-Trench Georgia, Berchuck Andrew, Pearce C Leigh, Whittemore Alice S, Menon Usha, Pharoah Paul D P, Gayther Simon A, Ramus Susan J
Abstract excerpt
Common germline genetic variation in the population is associated with susceptibility to epithelial ovarian cancer. Microcell-mediated chromosome transfer and expression microarray analysis identified nine genes associated with functional suppression of tumorogenicity in ovarian cancer cell lines; AIFM2, AKTIP, AXIN2, CASP5, FILIP1L, RBBP8, RGC32, RUVBL1 and STAG3. Sixty-three tagging single nucleotide...
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