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Article

Effects of common germ-line genetic variation in cell cycle genes on ovarian cancer survival.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Feb 2008

Song Honglin, Hogdall Estrid, Ramus Susan J, Dicioccio Richard A, Hogdall Claus, Quaye Lydia, McGuire Valerie, Whittemore Alice S, Shah Mitul, Greenberg David, Easton Douglas F, Kjaer Susanne Kruger, Pharoah Paul D P, Gayther Simon A

Abstract excerpt

PURPOSE: Somatic alterations have been shown to correlate with ovarian cancer prognosis and survival, but less is known about the effects on survival of common inherited genetic variation. Of particular interest are genes involved in cell cycle pathways, which regulate cell division and could plausibly influence clinical characteristics of multiple tumors types. EXPERIMENTAL DESIGN: We examined associations...

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Identifiers

PMID: 18281541
DOI: 10.1158/1078-0432.CCR-07-1195
PMCID: PMC2430032

Genes

CCND2
CCNE1
CCND1
CCND3
CDK2
CDK4
CDK6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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