Article
Nef mutations in long-term non-progressors from former plasma donors infected with HIV-1 subtype B in China.
Biomedical and environmental sciences : BES - 1 Dec 2008
Wang Shu-Hua, Xing Hui, He Xiang, Zhu Feng-Xia, Meng Zhe-Feng, Ruan Yu-Hua, Shao Yi-Ming
Abstract excerpt
OBJECTIVE: To study the specific amino acid variation in Nef that may be related to disease progression after infection with HIV-1 subtype B, a predominant strain circulating in China, and to determine whether changes in Nef secondary structure may influence different stages of AIDS development based on the concept that the Nef gene of HIV infection dramatically alter the severity of viral infection and virus...
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