Article
Mutations in the nef and vif genes associated with progression to AIDS in elite controller and slow-progressor patients.
Journal of medical virology - 1 Apr 2013
Cruz Nadia V G, Amorim Raquel, Oliveira Fátima E, Speranza Francisco A C, Costa Luciana J
Abstract excerpt
Progression towards AIDS can vary from 5 to 10 years from the establishment of the primary infection by HIV-1 to more than 10 years in the complete absence of antiretroviral therapy. Several factors can contribute to the outcome of HIV infection, including host genetic and viral replicating characteristics. Historically, nef-deleted viral genomes have been associated with disease progression. Therefore, the...
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