Human immunodeficiency virus type 1 long-term non-progressors: the viral, genetic and immunological basis for disease non-progression.

Abstract excerpt

A small subset of human immunodeficiency virus type 1 (HIV-1)-infected, therapy-naive individuals--referred to as long-term non-progressors (LTNPs)--maintain a favourable course of infection, often being asymptomatic for many years with high CD4(+) and CD8(+) T-cell counts (>500 cells  μl(-1)) and low plasma HIV-RNA levels (<10 ,000 copies ml(-1)). Research in the field has undergone considerable development in...

Topics

• Anti-HIV Agents
• Disease Progression
• Genetic Predisposition to Disease
• HIV Infections
• HIV Long-Term Survivors
• HIV-1
• Humans
• Time Factors