Article
Genetic analysis of Indian HIV-1 nef: subtyping, variability and implications.
Microbes and infection - 1 Mar 2004
Jere Abhay, Tripathy Srikanth, Agnihotri Kalpana, Jadhav Sushama, Paranjape Ramesh
Abstract excerpt
HIV-1 subtype C is predominant in India and globally. In the present study, we analyze HIV-1 subtype C regulatory protein Nef sequences from five recent Indian seroconverters and five long-term survivors (LTSs) for variability at crucial functional domains. Sequence analysis suggested the possibility of using regulatory gene sequences for viral subtyping and evolutionary studies apart from structural genes. In...
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