Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

TGFB1 and TGFBR2 functional polymorphisms and risk of esophageal squamous cell carcinoma: a case-control analysis in a Chinese population.

Journal of cancer research and clinical oncology - 1 Mar 2008

Jin Guangfu, Deng Yimei, Miao Ruifen, Hu Zhibin, Zhou Yan, Tan Yongfei, Wang Jianming, Hua Zhaolai, Ding Weiliang, Wang Lina, Chen Wensen, Shen Jing, Wang Xinru, Xu Yaochu, Shen Hongbing

Abstract excerpt

PURPOSE: Transforming growth factor beta1 (TGF-beta1) and its receptor II (TGF-betaRII) are two key components of TGF-beta signaling and play an important role in carcinogenesis. Several functional polymorphisms were identified in TGFB1 and TGFBR2 and associated with elevated serum or plasma level of TGF-beta1 and enhanced transcription activity of TGFBR2. This population-based case-control study was to evaluate...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asian People
Share to Carcinoma, Squamous Cell

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Esophageal Neoplasms

Share to Protein Serine-Threonine Kinases

Share to Receptor, Transforming Growth Factor-beta Type II

Share to Receptors, Transforming Growth Factor beta

Share to Transforming Growth Factor beta1

Source

Identifiers

PMID: 17680270
DOI: 10.1007/s00432-007-0290-1

Genes

TGFBR2
TGFB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

TGFB1 and TGFBR2 functional polymorphisms and risk of esophageal squamous cell carcinoma: a case-control analysis in a Chinese population.PMID 17680270Read ↗

Variant alleles of TGFB1 and TGFBR2 are associated with a decreased risk of gastric cancer in a Chinese population.Semantic proximity Read ↗

Association between the TGFB1 -509C/T and TGFBR2 -875A/G polymorphisms and gastric cancer: a case-control studySemantic proximity Read ↗

Genetic variation in transforming growth factor-beta1 gene associated with increased risk of esophageal squamous cell carcinoma.Semantic proximity Read ↗

Association between the TGFBR2 G-875A polymorphism and cancer risk: evidence from a meta-analysis.Semantic proximity Read ↗

[Correlations of polymorphisms of TGFB1 and TGFBR2 genes to genetic susceptibility to gastric cancer].Semantic proximity Read ↗

TGFβ-1 and TGFBR2 polymorphisms, cooking oil fume exposure and risk of lung adenocarcinoma in Chinese nonsmoking females: a case control study.Semantic proximity Read ↗

TGFBR1 tagging SNPs and gastric cancer susceptibility: a two-stage case-control study in Chinese population.Semantic proximity Read ↗

Correlation of <i>transforming growth factor beta‐1</i> gene polymorphisms C‐509T and T869C and the risk of gastric cancer in ChinaSemantic proximity Read ↗

Pathway analyses identify TGFBR2 as potential breast cancer susceptibility gene: results from a consortium study among Asians.Semantic proximity Read ↗

Influence of TGFB1 C-509T polymorphism on gastric cancer risk associated with TGF-β1 expression in the gastric mucosa.Semantic proximity Read ↗

Association between TGFBR1 polymorphisms and cancer risk: a meta-analysis of 35 case-control studies.Semantic proximity Read ↗

Polymorphisms in TGF-beta1 gene and the risk of lung cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.